r-dsb 2.0.0
Normalize & denoise droplet single cell protein data (CITE-Seq)
R-dsb improves protein expression analysis in droplet-based single-cell studies. The package specifically addresses noise in raw protein UMI counts from methods like CITE-seq. It identifies and removes two main sources of noise—protein-specific noise from unbound antibodies and droplet/cell-specific noise. The package is applicable to various methods, including CITE-seq, REAP-seq, ASAP-seq, TEA-seq, and Mission Bioplatform data. Check the vignette for tutorials on integrating dsb with Seurat and Bioconductor, and using dsb in Python.
- Outputs:
out - Website: https://github.com/niaid/dsb
- Licenses: CC0
- Package source: gnu/packages/bioconductor.scm
- Builds: See build status
- Issues: See known issues
Installation
Install r-dsb 2.0.0 as follows:
guix install r-dsb@2.0.0
Or install the latest version:
guix install r-dsb
You can also install packages in augmented, pure or containerized environments for development or simply to try them out without polluting your user profile. See the guix shell documentation for more information.