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r-awst

Asymmetric within-sample transformation

This package awst (Asymmetric Within-Sample Transformation) that regularizes RNA-seq read counts and reduces the effect of noise on the classification of samples. AWST comprises two main steps: standardization and smoothing. These steps transform gene expression data to reduce the noise of the lowly expressed features, which suffer from background effects and low signal-to-noise ratio, and the influence of the highly expressed features, which may be the result of amplification bias and other experimental artifacts.

Installation

Install the latest version of r-awst as follows:

guix install r-awst

Or install a particular version:

guix install r-awst@1.14.0

You can also install packages in augmented, pure or containerized environments for development or simply to try them out without polluting your user profile. See the guix shell documentation for more information.

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