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r-bseqsc

Deconvolution of bulk sequencing experiments using single cell data

BSeq-sc is a bioinformatics analysis pipeline that leverages single-cell sequencing data to estimate cell type proportion and cell type-specific gene expression differences from RNA-seq data from bulk tissue samples. This is a companion package to the publication "A single-cell transcriptomic map of the human and mouse pancreas reveals inter- and intra-cell population structure." Baron et al. Cell Systems (2016) https://www.ncbi.nlm.nih.gov/pubmed/27667365.

Installation

Install the latest version of r-bseqsc as follows:

guix install r-bseqsc

Or install a particular version:

guix install r-bseqsc@1.0-1.fef3f3e

You can also install packages in augmented, pure or containerized environments for development or simply to try them out without polluting your user profile. See the guix shell documentation for more information.