r-decoupler
Computational methods to infer biological activities from omics data
Many methods allow us to extract biological activities from omics data using information from prior knowledge resources, reducing the dimensionality for increased statistical power and better interpretability. decoupleR is a Bioconductor package containing different statistical methods to extract these signatures within a unified framework. decoupleR allows the user to flexibly test any method with any resource. It incorporates methods that take into account the sign and weight of network interactions. decoupleR can be used with any omic, as long as its features can be linked to a biological process based on prior knowledge. For example, in transcriptomics gene sets regulated by a transcription factor, or in phospho-proteomics phosphosites that are targeted by a kinase.
- Versions: 2.12.0
- Website: https://saezlab.github.io/decoupleR/
- Licenses: GPL 3
- Package source: gnu/packages/bioconductor.scm
- Builds: See build status
- Issues: See known issues
Installation
Install the latest version of r-decoupler as follows:
guix install r-decoupler
Or install a particular version:
guix install r-decoupler@2.12.0
You can also install packages in augmented, pure or containerized environments for development or simply to try them out without polluting your user profile. See the guix shell documentation for more information.
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