r-dmrseq
Detection and inference of differentially methylated regions
This package implements an approach for scanning the genome to detect and perform accurate inference on differentially methylated regions from Whole Genome Bisulfite Sequencing data. The method is based on comparing detected regions to a pooled null distribution, that can be implemented even when as few as two samples per population are available. Region-level statistics are obtained by fitting a generalized least squares (GLS) regression model with a nested autoregressive correlated error structure for the effect of interest on transformed methylation proportions.
- Versions: 1.28.0
- Website: https://bioconductor.org/packages/dmrseq
- Licenses: Expat
- Package source: gnu/packages/bioconductor.scm
- Builds: See build status
- Issues: See known issues
Installation
Install the latest version of r-dmrseq as follows:
guix install r-dmrseq
Or install a particular version:
guix install r-dmrseq@1.28.0
You can also install packages in augmented, pure or containerized environments for development or simply to try them out without polluting your user profile. See the guix shell documentation for more information.
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